Sepsis surveillance: an examination of parameter sensitivity and alert reliability.

ABSTRACT:

Objective

To examine performance of a sepsis surveillance system in a simulated environment where modifications to parameters and settings for identification of at-risk patients can be explored in-depth.

Materials and methods

This was a multiple center observational cohort study. The study population comprised 14 917 adults hospitalized in 2016. An expert-driven rules algorithm was applied against 15.1 million data points to simulate a system with binary notification of sepsis events. Three system scenarios were examined: a scenario as derived from the second version of the Consensus Definitions for Sepsis and Septic Shock (SEP-2), the same scenario but without systolic blood pressure (SBP) decrease criteria (near SEP-2), and a conservative scenario with limited parameters.

SUBMITTER: Amland RC 

PROVIDER: S-EPMC6951868 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature