Dissemination of the bla_NDM-5 Gene via IncX3-Type Plasmid among Enterobacteriaceae in Children.

ABSTRACT: The continuous emergence of novel New Delhi metallo-β-lactamase-5 (NDM-5)-producing Enterobacteriaceae isolates is receiving more and more public attention. Twenty-two NDM-5-producing strains were identified from 146 carbapenemase-producing Enterobacteriaceae (CRE) strains isolated from pediatric patients between January and March 2017, indicating that the bla_NDM-5 gene has spread to children. All 22 isolates, including 16 Klebsiella pneumoniae strains, four Klebsiella aerogenes strains, and two Escherichia coli strains, showed significantly high resistance to β-lactam antibiotics (except aztreonam) but remained susceptible to tigecycline and colistin. K. pneumoniae and K. aerogenes strains were respectively defined as homo

SUBMITTER: Tian D 

PROVIDER: S-EPMC6952193 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature