Reconsidering the prognostic significance of tumour deposit count in the TNM staging system for colorectal cancer.

ABSTRACT: Although the occurrence of tumour deposits (TDs) without metastatic lymph nodes (mLNs) is classified as "N1c" in the 8^th TNM staging system for colorectal cancer (CRC), the prognostic significance of the TD count is still controversial. A total of 39155 CRC patients were collected from the Surveillance, Epidemiology, and End Results (SEER) database. The potential associations between baseline characteristics and TD status were evaluated using the χ² test. Cancer-specific survival (CSS) rates were calculated by using the Kaplan-Meier method, and CSS comparisons were performed by using the log-rank test. The results showed that TD count was an important prognostic factor and that the number of TDs was negatively correlated with the prognosis of CRC patients. We found th

SUBMITTER: Wang S 

PROVIDER: S-EPMC6952424 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature