BRCA testing in unaffected young women in the United States, 2006-2017.

ABSTRACT:

Background

The discovery of the BRCA gene in the 1990s created an opportunity for individualized cancer prevention. BRCA testing in young women before cancer onset enables early detection of those with an increased cancer risk and creates an opportunity to offer lifesaving prophylactic procedures and medications. This study assessed trends in BRCA testing in women younger than 40 years without diagnosed breast or ovarian cancer (unaffected young women [UYW]) for cancer prevention between 2006 and 2017 in the United States.

Methods

This study included 93,278 adult women 18 to 65 years old with insurance claims for BRCA testing between 2006 and 2017 from the de-identified Optum Clinformatics Data Mart database. The data contained medical claims and administrative information f

SUBMITTER: Guo F 

PROVIDER: S-EPMC6952576 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature