MicroRNAs as Prognostic Markers in Acute Coronary Syndrome Patients-A Systematic Review.

ABSTRACT: : Background: The potential utility of microRNAs (miRNAs) in the diagnosis, prognosis, and treatment of multiple disease states has been an area of great interest since their discovery. In patients with cardiovascular disease, there is a large pool of literature amassed from the last decade assessing their diagnostic and prognostic potential. This systematic review sought to determine whether existing literature supports the use of miRNAs as prognostic markers after an Acute Coronary Syndrome (ACS) presentation. Methods: A systematic review of published articles from 2005-2019 using MEDLINE and EMBASE databases was undertaken independently by two reviewers. Studies addressing prognosis in an ACS population yielded 32 studies and 2 systematic reviews. Results/conclusion: 23 prospective stud

SUBMITTER: Barraclough JY 

PROVIDER: S-EPMC6952952 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature