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Magnesium for treating sickle cell disease.


ABSTRACT:

SUBMITTER: Than NN 

PROVIDER: S-EPMC6953350 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature

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Magnesium for treating sickle cell disease.

Than Nan Nitra NN   Soe Htoo Htoo Kyaw HHK   Palaniappan Senthil K SK   Abas Adinegara Bl AB   De Franceschi Lucia L  

The Cochrane database of systematic reviews 20190909


<h4>Background</h4>Sickle cell disease is an autosomal recessive inherited haemoglobinopathy which causes painful vaso-occlusive crises due to sickle red blood cell dehydration. Vaso-occlusive crises are common painful events responsible for a variety of clinical complications; overall mortality is increased and life expectancy decreased compared to the general population. Experimental studies suggest that intravenous magnesium has proven to be well-tolerated in individuals hospitalised for the  ...[more]

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