Ontology highlight
ABSTRACT:
SUBMITTER: Than NN
PROVIDER: S-EPMC6953350 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Than Nan Nitra NN Soe Htoo Htoo Kyaw HHK Palaniappan Senthil K SK Abas Adinegara Bl AB De Franceschi Lucia L
The Cochrane database of systematic reviews 20190909
<h4>Background</h4>Sickle cell disease is an autosomal recessive inherited haemoglobinopathy which causes painful vaso-occlusive crises due to sickle red blood cell dehydration. Vaso-occlusive crises are common painful events responsible for a variety of clinical complications; overall mortality is increased and life expectancy decreased compared to the general population. Experimental studies suggest that intravenous magnesium has proven to be well-tolerated in individuals hospitalised for the ...[more]