Simple non-mydriatic retinal photography is feasible and demonstrates retinal microvascular dilation in Chronic Obstructive Pulmonary Disease (COPD).

ABSTRACT:

Background

Chronic Obstructive Pulmonary Disease (COPD) is associated with an increased risk of myocardial infarction and stroke but it remains unclear how to identify microvascular changes in this population.

Objectives

We hypothesized that simple non-mydriatic retinal photography is feasible and can be used to assess microvascular damage in COPD.

Methods

Novel Vascular Manifestations of COPD was a prospective study comparing smokers with and without COPD, matched for age. Non-mydriatic, retinal fundus photographs were assessed using semi-automated software.

Results

Retinal images from 24 COPD and 22 control participants were compared. Cases were of similar age to controls (65.2 vs. 63.1 years, p = 0.38), had significantly lower Forced Expiratory Volume in one

SUBMITTER: McKay GJ 

PROVIDER: S-EPMC6953864 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature