Long-term Risk of Colorectal Cancer After Removal of Conventional Adenomas and Serrated Polyps.

ABSTRACT:

Background & aims

Endoscopic screening reduces incidence and mortality of colorectal cancer (CRC) because precursor lesions, such as conventional adenomas or serrated polyps, are removed. Individuals with polypectomies are advised to undergo colonoscopy surveillance to prevent CRC. However, guidelines for surveillance intervals after diagnosis of a precursor lesion, particularly for individuals with serrated polyps, vary widely, and lack sufficient supporting evidence. Consequently, some high-risk patients do not receive enough surveillance and lower-risk subjects receive excessive surveillance.

Methods

We examined the association between findings from first endoscopy and CRC risk among 122,899 participants who underwent flexible sigmoidoscopy or colonoscopy in the Nurses' H

SUBMITTER: He X 

PROVIDER: S-EPMC6954345 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature