A pilot randomized controlled trial of exercise to improve cognitive performance in patients with stable glioma: a proof of concept.

ABSTRACT:

Background

Patients with glioma often suffer from cognitive deficits. Physical exercise has been effective in ameliorating cognitive deficits in older adults and neurological patients. This pilot randomized controlled trial (RCT) explored the possible impact of an exercise intervention, designed to improve cognitive functioning in glioma patients, regarding cognitive test performance and patient-reported outcomes (PROs).

Methods

Thirty-four clinically stable patients with World Health Organization grades II/III glioma were randomized to a home-based remotely coached exercise group or an active control group. Patients exercised 3 times per week for 20-45 minutes, with moderate to vigorous intensity, during 6 months. At baseline and immediate follow-up, cognitive performance a

SUBMITTER: Gehring K 

PROVIDER: S-EPMC6954415 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature