Computational resources associating diseases with genotypes, phenotypes and exposures.

ABSTRACT: The causes of a disease and its therapies are not only related to genotypes, but also associated with other factors, including phenotypes, environmental exposures, drugs and chemical molecules. Distinguishing disease-related factors from many neutral factors is critical as well as difficult. Over the past two decades, bioinformaticians have developed many computational resources to integrate the omics data and discover associations among these factors. However, researchers and clinicians are experiencing difficulties in choosing appropriate resources from hundreds of relevant databases and software tools. Here, in order to assist the researchers and clinicians, we systematically review the public computational resources of human diseases related to genotypes, phenotypes, environment factor

SUBMITTER: Zhang W 

PROVIDER: S-EPMC6954426 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature