PennPET Explorer: Human Imaging on a Whole-Body Imager.

ABSTRACT: The PennPET Explorer, a prototype whole-body imager currently operating with a 64-cm axial field of view, can image the major body organs simultaneously with higher sensitivity than that of commercial devices. We report here the initial human imaging studies on the PennPET Explorer, with each study designed to test specific capabilities of the device. Methods: Healthy subjects were imaged with FDG on the PennPET Explorer. Subsequently, clinical subjects with disease were imaged with ¹⁸F-FDG and ⁶⁸Ga-DOTATATE, and research subjects were imaged with experimental radiotracers. Results: We demonstrated the ability to scan for a shorter duration or, alternatively, with less activity, without a compromise in image quality. Delayed images, up to 10 half-lives w

SUBMITTER: Pantel AR 

PROVIDER: S-EPMC6954463 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature