E-test versus agar dilution for antibiotic susceptibility testing of Helicobacter pylori: a comparison study.

ABSTRACT:

Objective

For evaluating the antibiotic resistance of Helicobacter pylori, the agar dilution method is the gold standard; however, using this method in daily practice is laborious. E-test has been proposed to be an uncomplicated method. This study was aimed at validating the E-test and detecting the presence of any bias between the agar dilution method and E-test.

Results

The agar dilution method and E-test were performed using five antibiotics for 72 strains of H. pylori obtained from clinical patients in Indonesia. The E-test's results showed a higher prevalence of resistance to all the antibiotics tested but the difference was not significant. Results showed high essential agreement (> 90.0%) for all the antibiotics, but only 84.7% for metronidazole. The agreement for MIC

SUBMITTER: Miftahussurur M 

PROVIDER: S-EPMC6954499 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature