Kidney function and nephrotoxic drug use among older home-dwelling persons with or without diabetes in Finland.

ABSTRACT:

Background

Due to these changes in kidney function, aging kidneys are more prone to drug-induced impairments in renal properties. Diabetes has been associated with the declined kidney function and an elevated risk of renal failure. The aim of this study is to compare kidney function and potentially nephrotoxic drug use among home-dwelling older persons with or without diabetes.

Methods

A total of 259 persons with and 259 persons without diabetes and aged ≥65 years were randomly selected to participate in a health examination with complete data gathered from 363 individuals (187 with diabetes and 176 without diabetes). The estimated glomerular filtration rate (eGFR) was calculated using CKD-EPI equation. Each participant was categorized based on the nephrotoxic profile of the

SUBMITTER: Heinjoki M 

PROVIDER: S-EPMC6954600 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature