Effect of early palliative care for patients with glioblastoma (EPCOG): a randomised phase III clinical trial protocol.

ABSTRACT: ​INTRODUCTION: Randomised controlled trials (RCTs) have shown a positive effect of early integration of palliative care (EIPC) in various advanced cancer entities regarding patients' quality of life (QoL), survival, mood, caregiver burden and reduction of aggressiveness of treatment near the end of life. However, RCTs investigating the positive effect of EIPC for patients suffering from glioblastoma multiforme (GBM) are lacking. After modelling work identifying the specific needs of GBM patients and their caregivers, the aim of this study is to investigate the impact of EIPC in this particular patient group. ​METHODS AND ANALYSIS: The recruitment period of this multicenter RCT started in May 2019. GBM patients (n=214) and their caregivers will be randomly assigned to either the interventio

SUBMITTER: Golla H 

PROVIDER: S-EPMC6955518 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature