Association between H. pylori infection and health Outcomes: an umbrella review of systematic reviews and meta-analyses.

ABSTRACT:

Objective

Systematic reviews and meta-analyses have revealed the associations between H. pylori infection and various health outcomes. We aimed to evaluate the strength and breadth of evidence on the associations.

Design

Umbrella review of systematic reviews and meta-analyses.

Setting

No settings.

Participants

No patients involved.

Data sources

Embase, PubMed, Web of Science, Cochrane Library Databases, CNKI, VIP database and Wangfang database from inception to February 1, 2019.

Outcomes measures

Diverse diseases (such as cancer and ischaemic heart disease).

Results

Sixty articles reporting 88 unique outcomes met the eligible criteria. 74 unique outcomes had nominal significance (p<0.05). Of the outcomes with significance, 61 had har

SUBMITTER: Li L 

PROVIDER: S-EPMC6955574 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature