Endothelin receptor antagonists for pulmonary arterial hypertension.

ABSTRACT:

Background

Pulmonary arterial hypertension is a devastating disease, which leads to right heart failure and premature death. Recent evidence suggests that endothelin receptor antagonists may be promising drugs in the treatment of pulmonary arterial hypertension.

Objectives

To evaluate the efficacy of endothelin receptor antagonists in pulmonary arterial hypertension.

Search methods

We searched CENTRAL (Cochrane Central Register of Controlled Trials), MEDLINE, EMBASE, and the reference section of retrieved articles. Searches are current as of January 2012.

Selection criteria

We included randomised trials (RCTs) and quasi-randomised trials involving patients with pulmonary arterial hypertension.

Data collection and analysis

Five review authors independentl

SUBMITTER: Liu C 

PROVIDER: S-EPMC6956416 | biostudies-literature | 2013 Feb

REPOSITORIES: biostudies-literature