Enhancement of 1,3-propanediol production from industrial by-product by Lactobacillus reuteri CH53.

ABSTRACT: BACKGROUND:1,3-propanediol (1,3-PDO) is the most widely studied value-added product that can be produced by feeding glycerol to bacteria, including Lactobacillus sp. However, previous research reported that L. reuteri only produced small amounts and had low productivity of 1,3-PDO. It is urgent to develop procedures that improve the production and productivity of 1,3-PDO. RESULTS:We identified a novel L. reuteri CH53 isolate that efficiently converted glycerol into 1,3-PDO, and performed batch co-fermentation with glycerol and glucose to evaluate its production of 1,3-PDO and other products. We optimized the fermentation conditions and nitrogen sources to increase the productivity. Fed-batch fermentation using corn steep liquor (CSL) as a replacement for beef extract led to 1,3-PDO product

SUBMITTER: Ju JH 

PROVIDER: S-EPMC6956512 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature