ICn3D, a web-based 3D viewer for sharing 1D/2D/3D representations of biomolecular structures.

ABSTRACT:

Motivation

Build a web-based 3D molecular structure viewer focusing on interactive structural analysis.

Results

iCn3D (I-see-in-3D) can simultaneously show 3D structure, 2D molecular contacts and 1D protein and nucleotide sequences through an integrated sequence/annotation browser. Pre-defined and arbitrary molecular features can be selected in any of the 1D/2D/3D windows as sets of residues and these selections are synchronized dynamically in all displays. Biological annotations such as protein domains, single nucleotide variations, etc. can be shown as tracks in the 1D sequence/annotation browser. These customized displays can be shared with colleagues or publishers via a simple URL. iCn3D can display structure-structure alignments obtained from NCBI's VAST+ service. It ca

SUBMITTER: Wang J 

PROVIDER: S-EPMC6956771 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature