Antimicrobial resistant enteric bacteria are widely distributed amongst people, animals and the environment in Tanzania.

ABSTRACT: Antibiotic use and bacterial transmission are responsible for the emergence, spread and persistence of antimicrobial-resistant (AR) bacteria, but their relative contribution likely differs across varying socio-economic, cultural, and ecological contexts. To better understand this interaction in a multi-cultural and resource-limited context, we examine the distribution of antimicrobial-resistant enteric bacteria from three ethnic groups in Tanzania. Household-level data (n = 425) was collected and bacteria isolated from people, livestock, dogs, wildlife and water sources (n = 62,376 isolates). The relative prevalence of different resistance phenotypes is similar across all sources. Multi-locus tandem repeat analysis (n = 719) and whole-genome sequencing (n = 816) of Escherichia coli demonst

SUBMITTER: Subbiah M 

PROVIDER: S-EPMC6957491 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature