Clinicopathological characteristics and survival outcomes of patients with coexistence of adenomyosis and endometrial carcinoma.

ABSTRACT: OBJECTIVE:To examine the association of coexistence of adenomyosis and endometrial carcinoma on tumor characteristics and survival outcome of patients. METHODS:Clinical and pathological data were retrospectively reviewed from 1584 patients who underwent surgical treatment of endometrial carcinoma. Statistical analyses were performed to evaluate associations of the presence or absence of adenomyosis with demographics, clinical parameters, histopathological factors, and survival outcomes. RESULTS:Adenomyosis was found in 150/1584 patients, and was significantly associated with premenopausal status (46% vs. 35.15%, P = 0.008), younger age (60.67% vs. 41.92% < 55 years old, P < 0.001), lower positive p53 expression (53.36% vs. 63.32%, P = 0.034), earlier disease stage (I-II) (92.67% vs. 85.56%

SUBMITTER: Zhang Z 

PROVIDER: S-EPMC6958044 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature