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Rotavirus Vaccination Is Associated With Reduced Seizure Hospitalization Risk Among Commercially Insured US Children.

ABSTRACT: Rotavirus commonly causes diarrhea but can also cause seizures. Analysis of insurance claims for 1773295 US children with 2950 recorded seizures found that, compared to rotavirus-unvaccinated children, seizure hospitalization risk was reduced by 24% (95% confidence interval [CI], 13%-33%) and 14% (95% CI, 0%-26%) among fully and partially rotavirus-vaccinated children, respectively.

SUBMITTER: Burke RM 

PROVIDER: S-EPMC6958696 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature

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Rotavirus Vaccination Is Associated With Reduced Seizure Hospitalization Risk Among Commercially Insured US Children.

Burke Rachel M RM   Tate Jacqueline E JE   Dahl Rebecca Moritz RM   Aliabadi Negar N   Parashar Umesh D UD  

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20181001 10

Rotavirus commonly causes diarrhea but can also cause seizures. Analysis of insurance claims for 1773295 US children with 2950 recorded seizures found that, compared to rotavirus-unvaccinated children, seizure hospitalization risk was reduced by 24% (95% confidence interval [CI], 13%-33%) and 14% (95% CI, 0%-26%) among fully and partially rotavirus-vaccinated children, respectively. ...[more]

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