Racial disparities in chemotherapy administration for early-stage breast cancer: a systematic review and meta-analysis.

ABSTRACT:

Purpose

We conducted a systematic review and meta-analysis to measure the extent to which race is associated with delayed initiation or receipt of inadequate chemotherapy among women with early-stage breast cancer.

Methods

We performed a systematic search of all articles published from January 1987 until June 2017 within four databases: PubMed/Medline, EMBASE, CINAHL, and Cochrane CENTRAL. Eligible studies were US-based and examined the influence of race on chemotherapy delays, cessation, or dose reductions among women with stage I, II, or III breast cancer. Data were pooled using a random effects model.

Results

A total of twelve studies were included in the quantitative analysis. Blacks were significantly more likely than whites to have delays to initiation of adjuva

SUBMITTER: Green AK 

PROVIDER: S-EPMC6958704 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature