Comparison of three risk stratification models for non-clear cell renal cell carcinoma patients treated with temsirolimus as first-line therapy.

ABSTRACT:

Background/aims

For metastatic renal cell carcinoma (RCC), various prognostic scoring systems have been developed. However, owing to the low prevalence of nonclear cell RCC, the three most commonly used tools were mainly developed based on patients with clear cell histology. Accordingly, this study applied three prognostic models to Korean non-clear cell RCC patients treated with first-line temsirolimus.

Methods

This study analyzed data for 74 patients with non-clear cell RCC who were treated with temsirolimus as the first-line therapy at eight medical centers between 2011 and 2016. The receiver-operating characteristic (ROC) curves for the different prognostic models were analyzed.

Results

Twenty-seven (36.5%), 24 (32.4%), and 44 patients (59.5%) were assigned to the

SUBMITTER: Lee IH 

PROVIDER: S-EPMC6960037 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature