Statistical Analysis and Nucleation Parameter Estimation from Nucleation Experiments in Flowing Microdroplets.

ABSTRACT: We have studied the primary nucleation of adipic acid from aqueous solutions in thousands of microdroplets generated in a fully automated microfluidic setup. By varying supersaturation in solution and residence time, we were able to estimate nucleation rates and growth times, while accounting for the stochastic nature of nucleation, the variability in microdroplet volumes (which is kept below 2%, thanks to a carefully designed experimental protocol), and the uncertainty in the automated image analysis procedure. Through a thorough statistical analysis we have obtained exact expressions for the expected values and the variances of all the random variables involved, all the way to the nucleation rate and the growth time associated with each supersaturation level explored and to the model par

SUBMITTER: Dos Santos EC 

PROVIDER: S-EPMC6961308 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature