Enhanced genome assembly and a new official gene set for Tribolium castaneum.

ABSTRACT:

Background

The red flour beetle Tribolium castaneum has emerged as an important model organism for the study of gene function in development and physiology, for ecological and evolutionary genomics, for pest control and a plethora of other topics. RNA interference (RNAi), transgenesis and genome editing are well established and the resources for genome-wide RNAi screening have become available in this model. All these techniques depend on a high quality genome assembly and precise gene models. However, the first version of the genome assembly was generated by Sanger sequencing, and with a small set of RNA sequence data limiting annotation quality.

Results

Here, we present an improved genome assembly (Tcas5.2) and an enhanced genome annotation resulting in a new official gene

SUBMITTER: Herndon N 

PROVIDER: S-EPMC6961396 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature