Impacts of Sex Differences in Pulse Pressure among Patients with Chronic Kidney Disease.

ABSTRACT: Introduction: Though disease-related differences between the sexes have increasingly attracted attention, the renal impact of pulse pressure (PP) in patients with chronic kidney disease (CKD) has never been investigated comprehensively in relation to differences associated with sex. We aimed to examine sex differences in PP as a related factor of CKD progression from the perspective of atherosclerosis. Methods: A total of 156 patients with CKD matched according to age and estimated glomerular filtration rate (eGFR) were separated into sex-based cohorts. Multivariate Cox proportional hazards analyses were performed to identify factors associated with renal outcomes. Kaplan-Meier analyses were performed to assess disease progression, which was defined as a ≥50% estimated glomerular filtratio

SUBMITTER: Kataoka H 

PROVIDER: S-EPMC6963663 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature