A New Look at the Structures of Old Sepsis Actors by Exploratory Data Analysis Tools.

ABSTRACT: Sepsis is a life-threatening condition that accounts for numerous deaths worldwide, usually complications of common community infections (i.e., pneumonia, etc), or infections acquired during the hospital stay. Sepsis and septic shock, its most severe evolution, involve the whole organism, recruiting and producing a lot of molecules, mostly proteins. Proteins are dynamic entities, and a large number of techniques and studies have been devoted to elucidating the relationship between the conformations adopted by proteins and what is their function. Although molecular dynamics has a key role in understanding these relationships, the number of protein structures available in the databases is so high that it is currently possible to build data sets obtained from experimentally determined structu

SUBMITTER: Gnoni A 

PROVIDER: S-EPMC6963771 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature