Model-based exploration of the impact of glucose metabolism on the estrous cycle dynamics in dairy cows.

ABSTRACT:

Background

Nutrition plays a crucial role in regulating reproductive hormones and follicular development in cattle. This is visible particularly during the time of negative energy balance at the onset of milk production after calving. Here, elongated periods of anovulation have been observed, resulting from alterations in luteinizing hormone concentrations, likely caused by lower glucose and insulin concentrations in the blood. The mechanisms that result in a reduced fertility are not completely understood, although a close relationship to the glucose-insulin metabolism is widely supported.

Results

Following this idea, we developed a mathematical model of the hormonal network combining reproductive hormones and hormones that are coupled to the glucose compartments within the

SUBMITTER: Omari M 

PROVIDER: S-EPMC6964039 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature