Achievement of hepatitis C cascade of care milestones: a population-level analysis in Alberta, Canada.

ABSTRACT:

Objectives

Despite highly effective directly acting antiviral (DAA) therapy for hepatitis C virus (HCV), many patients do not receive treatment. We characterized the achievement of cascade of care milestones within 2 years of diagnosis among the Alberta population and evaluated variables associated with engagement at each stage.

Methods

All Albertans with a first-time positive HCV antibody between 2009 and 2014 were included in this retrospective study. We determined which patients received follow-up testing (HCV RNA and HCV genotype), referral to hepatitis specialty care, and antiviral prescription, and achieved SVR within 2 years of diagnosis. Factors associated with achieving cascade milestones were identified by multivariable logistic regression analysis.

Results

SUBMITTER: O'Neil CR 

PROVIDER: S-EPMC6964571 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature