Preliminary evaluation of a novel nine-biomarker profile for the prediction of autism spectrum disorder.

ABSTRACT:

Background

Autism spectrum disorder (ASD) is a complex group of heterogeneous neurodevelopmental disorders the prevalence of which has been in the rise in the past decade. In an attempt to better target the basic causes of ASD for diagnosis and treatment, efforts to identify reliable biomarkers related to the body's metabolism are increasing. Despite an increase in identifying biomarkers in ASD, there are none so far with enough evidence to be used in routine clinical examination, unless medical illness is suspected. Promising biomarkers include those of mitochondrial dysfunction, oxidative stress, energy metabolism, and apoptosis.

Methods and participants

Sodium (Na+), Potassium (K+), glutathione (GSH), glutathione-s-transferase (GST), Creatine kinase (CK), lactate dehydrog

SUBMITTER: El-Ansary A 

PROVIDER: S-EPMC6964874 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature