Epidemiology of multiple sclerosis and vitamin D levels in Lanzarote, Canary Islands, Spain.

ABSTRACT:

Background

Low levels of 25-hydroxyvitamin D (25(OH)D) have been described as one of the possible environmental factors involved in multiple sclerosis (MS) etiopathogenesis.

Objectives

To study epidemiology of MS and 25(OH)D serum levels of patients in Lanzarote (29°02'06″N), a region with high ultraviolet radiation values during the whole year which is located far apart from Iberian Peninsula (36°-43°N), but without genetic/ethnic differences with it.

Methods

Incidence in Lanzarote was assessed according to McDonald 2005 criteria between January 2008 and December 2015 and prevalence date was 12/31/15. For 25(OH)D serum levels analyses, samples from 60 MS patients and 60 healthy donors (HD) were collected monthly in a one-year prospective study.

Results

The pre

SUBMITTER: Perez-Perez S 

PROVIDER: S-EPMC6966995 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature