The development of brain network hubs.

ABSTRACT: Some brain regions have a central role in supporting integrated brain function, marking them as network hubs. Given the functional importance of hubs, it is natural to ask how they emerge during development and to consider how they shape the function of the maturing brain. Here, we review evidence examining how brain network hubs, both in structural and functional connectivity networks, develop over the prenatal, neonate, childhood, and adolescent periods. The available evidence suggests that structural hubs of the brain arise in the prenatal period and show a consistent spatial topography through development, but undergo a protracted period of consolidation that extends into late adolescence. In contrast, the hubs of brain functional networks show a more variable topography, being predomi

SUBMITTER: Oldham S 

PROVIDER: S-EPMC6969262 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature