Do you know what I'm thinking? Temporal and spatial brain activity during a theory-of-mind task in children with autism.

ABSTRACT: The social impairments observed in children with autism spectrum disorder are thought to arise in part from deficits in theory of mind, the ability to understand other people's thoughts and feelings. To determine the temporal-spatial dynamics of brain activity underlying these atypical theory-of-mind processes, we used magnetoencephalography to characterize the sequence of functional brain patterns (i.e. when and where) related to theory-of-mind reasoning in 19 high-functioning children with autism compared to 22 age- and sex-matched typically-developing children aged 8-12 during a false-belief (theory-of-mind) task. While task performance did not differ between the two groups, children with autism showed reduced activation in the left temporoparietal junction between 300-375 and 425-500 m

SUBMITTER: Yuk V 

PROVIDER: S-EPMC6969351 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature