Bi-Layered Polymer Carriers with Surface Modification by Electrospinning for Potential Wound Care Applications.

ABSTRACT: Polymeric wound dressings with advanced properties are highly preferred formulations to promote the tissue healing process in wound care. In this study, a combinational technique was investigated for the fabrication of bi-layered carriers from a blend of polyvinyl alcohol (PVA) and sodium alginate (SA). The bi-layered carriers were prepared by solvent casting in combination with two surface modification approaches: electrospinning or three-dimensional (3D) printing. The bi-layered carriers were characterized and evaluated in terms of physical, physicochemical, adhesive properties and for the safety and biological cell behavior. In addition, an initial inkjet printing trial for the incorporation of bioactive substances for drug delivery purposes was performed. The solvent cast (SC) film ser

SUBMITTER: Palo M 

PROVIDER: S-EPMC6969931 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature