Global, regional, and national sepsis incidence and mortality, 1990-2017: analysis for the Global Burden of Disease Study.

ABSTRACT:

Background

Sepsis is life-threatening organ dysfunction due to a dysregulated host response to infection. It is considered a major cause of health loss, but data for the global burden of sepsis are limited. As a syndrome caused by underlying infection, sepsis is not part of standard Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) estimates. Accurate estimates are important to inform and monitor health policy interventions, allocation of resources, and clinical treatment initiatives. We estimated the global, regional, and national incidence of sepsis and mortality from this disorder using data from GBD 2017.

Methods

We used multiple cause-of-death data from 109 million individual death records to calculate mortality related to sepsis among each of the 282 un

SUBMITTER: Rudd KE 

PROVIDER: S-EPMC6970225 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature