Expression of ESR1 and ESR2 oestrogen receptor encoding gene and personality traits - preliminary study.

ABSTRACT:

Introduction

The main objective of the study is to examine the hypothesis claiming a correlation between personality traits measured with the use of the Minnesota Multiphasic Personality Inventory (MMPI-2) personality questionnaire and the expression of the ERα (ESR1) and ERβ (ESR2) encoding gene in patients suffering from depression.

Material and methods

The experiment was carried out on a group of 44 individuals with depression. The Polish variant of the MMPI-2 was applied with the aim of assessing personality traits. Furthermore, the authors evaluated the expression of the genes encoding the oestrogen receptors (ERα and ERβ) at the mRNA level and protein level in the studied population.

Results

No significant differences in the expression of ERα and E

SUBMITTER: Talarowska ME 

PROVIDER: S-EPMC6970415 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature