Clinical variables that increase the probability of pulmonary embolism diagnosis in symptomatic children.

ABSTRACT:

Background

Pulmonary embolism (PE) in children carries a significant morbidity and mortality. We examined previously described factors in 2 cohorts of children tested for PE and identified novel factors.

Methods

We combined data from 2 retrospective cohorts. Patients up to age 21 years were included who underwent imaging or D-dimer testing for PE, with positive radiologic testing being the gold standard. Combined predictor variables were examined by univariate analysis and then forward stepwise multivariable logistic regression.

Results

The combined data set yielded 1103 patients with 42 unique predictor variables, and 93 PE-positive patients (8.4%), with a median age of 16 years. Univariate analysis retained 17 variables, and multivariable logistic regression found 9

SUBMITTER: Hennelly KE 

PROVIDER: S-EPMC6971320 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature