WormQTL2: an interactive platform for systems genetics in Caenorhabditis elegans.

ABSTRACT: Quantitative genetics provides the tools for linking polymorphic loci to trait variation. Linkage analysis of gene expression is an established and widely applied method, leading to the identification of expression quantitative trait loci (eQTLs). (e)QTL detection facilitates the identification and understanding of the underlying molecular components and pathways, yet (e)QTL data access and mining often is a bottleneck. Here, we present WormQTL2, a database and platform for comparative investigations and meta-analyses of published (e)QTL data sets in the model nematode worm C. elegans. WormQTL2 integrates six eQTL studies spanning 11 conditions as well as over 1000 traits from 32 studies and allows experimental results to be compared, reused and extended upon to guide further experiments a

SUBMITTER: Snoek BL 

PROVIDER: S-EPMC6971878 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature