Asymptomatic intracranial aneurysms in beta-thalassemia: a three-year follow-up report.

ABSTRACT:

Background

No information is currently available regarding the natural history of asymptomatic intracranial aneurysms in beta-thalassemia, raising several concerns about their proper management.

Methods

We performed a prospective longitudinal three-year-long MR-angiography study on nine beta-thalassemia patients (mean-age 40.3 ± 7.5, six females, 8 transfusion dependent) harboring ten asymptomatic intracranial aneurysms. In addition, we analyzed the clinical files of all adult beta-thalassemia patients (160 patients including those followed with MR-angiography, 121 transfusion dependent) referring to our Centers between 2014 and 2019 searching for history of subarachnoid hemorrhage or history of symptomatic intracranial aneurysms.

Results

At the end of the three-year-

SUBMITTER: Manara R 

PROVIDER: S-EPMC6971974 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature