Thermal Stability and Explosive Hazard Assessment of Diazo Compounds and Diazo Transfer Reagents.

ABSTRACT: Despite their wide use in academia as metal-carbene precursors, diazo compounds are often avoided in industry owing to concerns over their instability, exothermic decomposition, and potential explosive behavior. The stability of sulfonyl azides and other diazo transfer reagents is relatively well understood, but there is little reliable data available for diazo compounds. This work first collates available sensitivity and thermal analysis data for diazo transfer reagents and diazo compounds to act as an accessible reference resource. Thermogravimetric analysis (TGA), differential scanning calorimetry (DSC), and accelerating rate calorimetry (ARC) data for the model donor/acceptor diazo compound ethyl (phenyl)diazoacetate are presented. We also present a rigorous DSC dataset with 43 other d

SUBMITTER: Green SP 

PROVIDER: S-EPMC6972035 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature