Variation in menopausal vasomotor symptoms outcomes in clinical trials: a systematic review.

ABSTRACT:

Background

There is substantial variation in how menopausal vasomotor symptoms are reported and measured among intervention studies. This has prevented meaningful comparisons between treatments and limited data synthesis.

Objectives

To review systematically the outcome reporting and measures used to assess menopausal vasomotor symptoms from randomised controlled trials of treatments.

Search strategy

We searched MEDLINE, Embase, and Cochrane Central Register of Controlled Trials from inception to May 2018.

Selection criteria

Randomised controlled trials with a primary outcome of menopausal vasomotor symptoms in women and a sample size of at least 20 women per study arm.

Data collection and analysis

Data about study characteristics, primary vasomotor-relat

SUBMITTER: Iliodromiti S 

PROVIDER: S-EPMC6972542 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature