Fabrication of tissue-engineered cell sheets by automated cell culture equipment.

ABSTRACT: Most cells for regenerative medicine are currently cultured manually. In order to promote the widespread use of regenerative medicine, it will be necessary to develop automated culture techniques so that cells can be produced in greater quantities at lower cost and with more stable quality. In the field of regenerative medicine technology, cell sheet therapy is an effective tissue engineering technique whereby cells can be grafted by attaching them to a target site. We have developed automated cell culture equipment to promote the use of this cell sheet regenerative treatment. This equipment features a fully closed culture vessel and circuit system that avoids contamination with bacteria and the like from the external environment, and it was designed to allow 10 cell sheets to be simultane

SUBMITTER: Nishimura A 

PROVIDER: S-EPMC6972683 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature