Clinical and epidemiological factors associated with spontaneous preterm birth: a multicentre cohort of low risk nulliparous women.

ABSTRACT: The objective of this study was to determine incidence and risk factors associated with spontaneous preterm birth (sPTB). It was a prospective multicentre cohort study performed in five Brazilian referral maternity hospitals and enrolling nulliparous women at 19-21 weeks. Comprehensive maternal data collected during three study visits were addressed as potentially associated factors for sPTB. Bivariate and multivariate analysis estimated risk ratios. The main outcomes measures were birth before 37 weeks due to spontaneous preterm labour or premature rupture of membranes (sPTB). The comparison group was comprised of women with term births (≥37weeks). Outcome data was available for 1,165 women, 6.7% of whom had sPTB, 16% had consumed alcohol and 5% had used other illicit drugs during the fir

SUBMITTER: Souza RT 

PROVIDER: S-EPMC6972868 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature