MicroRNA and mRNA interactions coordinate the immune response in non-lethal heat stressed Litopenaeus vannamei against AHPND-causing Vibrio parahaemolyticus.

ABSTRACT: While Vibrio parahaemolyticus (VP_AHPND) has been identified as the cause of early mortality syndrome (EMS) or acute hepatopancreatic necrosis disease (AHPND) in shrimp, mechanisms of host response remain unknown. Understanding these processes is important to improve farming practices because this understanding will help to develop methods to enhance shrimp immunity. Pre-treatment of shrimp with 5-minute chronic non-lethal heat stress (NLHS) for 7 days was found to significantly increase Litopenaeus vannamei survival against VP_AHPND infection. To elucidate the mechanism involved, mRNA and miRNA expression profiles from the hemocyte of L. vannamei challenged with VP_AHPND after NLHS with corresponding control conditions were determined by RNA-Seq. A total of 2

SUBMITTER: Boonchuen P 

PROVIDER: S-EPMC6972907 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature