Chemoenzymatic Halocyclization of γ,δ-Unsaturated Carboxylic Acids and Alcohols.

ABSTRACT: A chemoenzymatic method for the halocyclization of unsaturated alcohols and acids by using the robust V-dependent chloroperoxidase from Curvularia inaequalis (CiVCPO) as catalyst has been developed for the in situ generation of hypohalites. A broad range of halolactones and cyclic haloethers are formed with excellent performance of the biocatalyst.

SUBMITTER: Younes SHH 

PROVIDER: S-EPMC6973245 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature