Identification of pigments related to allergic tattoo reactions in 104 human skin biopsies.

ABSTRACT:

Background

Red tattoos are prone to allergic reactions. The identity of the allergen(s) is mostly unknown.

Objectives

Chemical analysis of human skin biopsies from chronic allergic reactions in red tattoos to identify culprit pigment(s) and metals.

Material and methods

One hundred four dermatome biopsies were analyzed by matrix-assisted laser desorption/ionization tandem mass spectrometry (MALDI-MS/MS) for identification of commonly used organic pigments. Metal concentrations were assessed by inductively coupled plasma (ICP)-MS and x-ray fluorescence (XRF). Fourteen patients had cross-reactions in other red tattoos.

Results

In total, the identified pigments were mainly azo Pigment Red (P.R.) 22 (35%), P.R. 210 (24%), P.R. 170 (12%), P.R. 5 (0.9%), P.R. 112 (0.9

SUBMITTER: Serup J 

PROVIDER: S-EPMC6973263 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature