Common Variable Immunodeficiency: A Standardized Patient Case for Second-Year Medical Students.

ABSTRACT: Introduction:Common variable immunodeficiency (CVID) is the most common symptomatic antibody deficiency, with a prevalence of 0.6-6.9 depending on the population studied. In contrast to other primary immunodeficiency diseases (PIDDs), symptoms may not appear until the third decade of life. Lack of recognition of CVID is a persistent problem. Myriad confounding clinical phenotypes and frequent infections, including autoimmunity, malignancy, chronic lung disease, granulomatous disease, and gastrointestinal disease, complicate the diagnosis. Often it is years before a diagnosis is made, leading to irreversible morbidities and mortality. Methods:Second-year medical students are introduced to CVID during their session on PIDDs that occurs during the immunology/rheumatology course. To assess stu

SUBMITTER: Barilla-LaBarca ML 

PROVIDER: S-EPMC6974347 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature