SmartGraph: a network pharmacology investigation platform.

ABSTRACT:

Motivation

Drug discovery investigations need to incorporate network pharmacology concepts while navigating the complex landscape of drug-target and target-target interactions. This task requires solutions that integrate high-quality biomedical data, combined with analytic and predictive workflows as well as efficient visualization. SmartGraph is an innovative platform that utilizes state-of-the-art technologies such as a Neo4j graph-database, Angular web framework, RxJS asynchronous event library and D3 visualization to accomplish these goals.

Results

The SmartGraph framework integrates high quality bioactivity data and biological pathway information resulting in a knowledgebase comprised of 420,526 unique compound-target interactions defined between 271,098 unique compound

SUBMITTER: Zahoranszky-Kohalmi G 

PROVIDER: S-EPMC6974502 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature