Clustering of asymptomatic Plasmodium falciparum infection and the effectiveness of targeted malaria control measures.

ABSTRACT: BACKGROUND:Because clustering of Plasmodium falciparum infection had been noted previously, the clustering of infection was examined at four field sites in West Africa: Dangassa and Dioro in Mali, Gambissara in The Gambia and Madina Fall in Senegal. METHODS:Clustering of infection was defined by the percent of persons with positive slides for asexual P. falciparum sleeping in a house which had been geopositioned. Data from each site were then tested for spatial, temporal and spatio-temporal clustering in relation to the prevalence of infection from smear surveys. RESULTS:These studies suggest that clustering of P. falciparum infection also affects the effectiveness of control interventions. For example, the clustering of infection in Madina Fall disappeared in 2014-2016 after vector contro

SUBMITTER: Shaffer JG 

PROVIDER: S-EPMC6975028 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature