A retrospective register study comparing fibrinogen treated trauma patients with an injury severity score matched control group.

ABSTRACT:

Background

Fibrinogen concentrate (FC) is frequently used to treat bleeding trauma patients, although the clinical effects are not well known. In this study we describe demographic and clinical outcome data in a cohort of trauma patients receiving FC, compared to a matched control group, who did not receive FC.

Methods

This retrospective, single-center, observational study included adult trauma patients admitted to a level 1-trauma center in Sweden between January 2013 and June 2015. The study population consisted of patients to whom FC was administrated within 24 h (n = 138, "Fib+"). Patients with Injury Severity Score (ISS) > 49 and/or deceased within 1 h from arrival were excluded (n = 30). Controls (n = 108) were matched for age, gender and ISS ("Fib-"). Primary outcome

SUBMITTER: Almskog LM 

PROVIDER: S-EPMC6975055 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature